The Use of Fluids in Sepsis

نویسندگان

  • Audrey A Avila
  • Eliezer C Kinberg
  • Nomi K Sherwin
  • Robinson D Taylor
چکیده

Sepsis is a systemic inflammatory response to severe infection causing significant morbidity and mortality that costs the health care system $20.3 billion annually within the United States. It is well established that fluid resuscitation is a central component of sepsis management; however, to date there is no consensus as to the ideal composition of fluid used for resuscitation. In this review, we discuss the progression of clinical research comparing various fluids, as well as the historical background behind fluid selection for volume resuscitation. We conclude that the use of balanced fluids, such as Ringer's Lactate, seems very promising but further research is needed to confirm their role.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Use of Serial C-reactive Protein Measure-ments for Determination of the Length of Empiric Antibiotic Therapy in Suspected Neonatal Sepsis

Background: The management of neonatal sepsis especially in developing countries is problematic.  There is no single reliable marker of infection available at the present.  C-reactive protein (CRP) has long been used as a marker of infection. Serial measurements of CRP are recommended as a guide for duration of antibiotic therapy. Objective: To evaluate the serial CRP measurement as a guideline...

متن کامل

Neonatal Sepsis: An Update

Sepsis is the most common cause of neonatal mortality. As per National Neonatal-Perinatal Database (NNPD), 2002-2003, the incidence of neonatal sepsis in India was 30 per 1000 live births. Signs and symptoms of sepsis are nonspecific; therefore empirical antimicrobial therapy is promptly initiated after obtaining appropriate cultures. The early manifestations of neonatal sepsis are vague and il...

متن کامل

Significance of Serum Procalcitonin Level in the Early Diagnosis of Neonatal Sepsis

Background: Sepsis in neonates presents itself with non-specific clinical features which makes early diagnosis difficult. However, procalcitonin (PCT) and other inflammatory markers have recently been considered as sensitive markers for the early detection of neonatal sepsis. Therefore, the present study aimed to determine the diagnostic value of PCT in the early detection of neonatal sepsis an...

متن کامل

Healthcare workers’ knowledge and strategies utilised for the prevention and management of neonatal sepsis in Nigeria

Background & aim: Sepsis is a major cause of neonatal mortality in the developing countries. The prevention and management of this infection require informed workforce and availability of necessary resources and equipment. Regarding this, the present study was conducted to investigate healthcare workers’ neonatal sepsis knowledge; prevention and management strategies in use for the control of t...

متن کامل

Investigating the Rate of Group B Streptococcus in Below 3 Months Year Old Infants with Sepsis Clinical Symptoms Hospitalized in Ghaem Hospital of Mashhad

Introduction Group B streptococcus is the main reason of neonatal infection in developed countries and causes a widespread clinical indications. In developing countries such as Iran, its rate of appearance is not determined. With regard to colonization and the relative high epithelia of group B streptococcus, it is likely that the incidence of group B streptococcus in neonatal sepsis is so high...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2016